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Results 1 - 8 of 8
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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP -
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP enzyme is important in the biosynthesis of mycothiol, which plays a role in protecting bacteria against oxidative stress
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP a key step in mycothiol, i.e. 1-D-myo-inosityl-2-(N-acetyl-L-cysteinyl)amido-2-deoxy-R-D-glucopyranoside or MSH or AcCys-GlcN-Ins, biosynthesis, mycothiol is produced to act against oxidative and antibiotic stress and is essential for cell growth, biosynthetic pathway, overview
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP key enzyme in the biosynthesis of mycothiol, pathway overview
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP the ATP-dependent ligation of Cys to GlcNIns is a key step in mycothiol biosynthesis, catalyzed by MshC, which is essential for growth of Mycobacterium tuberculosis
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP inactivation of the mshC gene in RHA1 results in the accumulation of the MSH pathway intermediate, 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside. The mutant is deficient in the biochemical degradation of a number of xenobiotics metabolized by the parent strain, it shows increased susceptibility to a number of antibiotics and it shows unusual growth characteristics, exhibiting a long lag phase before normal exponential growth
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.131-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP the product 1D-myo-inositol 2-(L-cysteinyl)amido-2-deoxy-alpha-D-glucopyranoside is an intermediate in the biosynthetic pathway of mycothiol. Mycothiol is produced by Mycobacterium tuberculosis to maintain an intracellular reducing environment and protect against oxidative and antibiotic induced stress. The biosynthesis of mycothiol is essential for cell growth
Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.13more penultimate enzyme in the mycothiol biosynthetic pathway
Results 1 - 8 of 8
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