EC Number |
Natural Substrates |
---|
5.3.3.12 | dopachrome |
melanin biosynthesis |
5.3.3.12 | L-dopachrome |
- |
5.3.3.12 | L-dopachrome |
Dct isomerizes the intermediate dopachrome to 5,6-dihydroxyindole-2-carboxylic acid, DHICA, and influences the proportion of DHICA monomer incorporated into the 5,6-dihydroxyindole, DHI, polymer in eumelanin |
5.3.3.12 | more |
existence of a common mechanism underlying radio- and chemoresistance, which is mediated by the enzyme |
5.3.3.12 | more |
role of enzyme in cytoprotection by preventing the production of atoxic melanin precursor, 5,6-dihydroxyindole |
5.3.3.12 | more |
isoforms of enzyme may play a part in the normal pathway of melamin biosynthesis |
5.3.3.12 | more |
DCT interacts with melanin |
5.3.3.12 | more |
MIF is a 12 kDa protein with an enzymatic keto-enol tautomerase activityMIF is a homotrimeric multifunctional proinflammatory cytokine. Binding of MIF to its receptor, CD74, overview |
5.3.3.12 | more |
MIF is a homotrimeric multifunctional proinflammatory cytokine. Binding of MIF to its receptor, CD74, overview |
5.3.3.12 | more |
the MIF protein is multifunctional, exhibiting besides its L-dopachrome tautomerase activity, e.g. also phenylpyruvate tautomerase activity, EC 5.3.2.1, and thioredoxin-like function, or its cytokine function, overview |