EC Number |
Natural Substrates |
---|
5.3.2.1 | (4-Hydroxyphenyl)pyruvate |
- |
5.3.2.1 | keto-(4-hydroxyphenyl)pyruvate |
- |
5.3.2.1 | keto-phenylpyruvate |
- |
5.3.2.1 | more |
role in the biosynthesis of thyroxine |
5.3.2.1 | more |
important immunoregulatory molecule with a unique ability to suppress the anti-inflammatory effects of glucocorticoids |
5.3.2.1 | more |
the enzymatic activity of macrophage migration inhibitory factor does not play a role in its migration inhibiting properties. Macrophage migration inhibitory factor is an inhibitor of the random migration of monocytes and macrophages and has since been proposed to have a number of immune and catalytic functions, macrophage migration inhibitory factor is an inhibitor of monocyte chemoattractant protein 1-induced chemotaxis of human peripheral blood monocytes |
5.3.2.1 | more |
the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF |
5.3.2.1 | more |
MIF is a homotrimeric multifunctional proinflammatory cytokine. It also shows dopachrome tautomerase activity. Binding of MIF to its receptor, CD74, overview |
5.3.2.1 | more |
the MIF protein is multifunctional, exhibiting besides its tautomerase activity, e.g. also L-dopachrome isomerase activity, EC 5.3.3.12, and thioredoxin-like function, or its cytokine function, overview |
5.3.2.1 | Phenylpyruvate |
- |