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Results 1 - 10 of 29 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more key enzyme for biosynthesis of N-acetylneuraminate is the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, catalyzing the first two steps of the biosynthesis in the cytosol
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more key enzyme of N-acetylneuraminic acid biosynthesis
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more rate-limiting step in sialic acid biosynthesis pathway. The enzyme is the major determinant of cell surface sialylation in hematopoietic cell lines and is a critical regulator of the function of specific cell surface adhesion molecules
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/ManNAc kinase catalyzes the first two steps in the biosynthesis of the sialic acids
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more the enzyme catalyzes the first step of sialic acid biosynthesis
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more downregulation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase in hyposialylated HIV-infected T cells with consequential glycosylation modification (the deficiency can be entirely corrected by nutrient complementation with N-acetylmannosamine). The promoter of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is de novo hypermethylated in HIV-infected CEM cells
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is a rate-limiting enzyme of sialic acid biosynthesis
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more the homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more biosynthesis of sialic acids
Show all pathways known for 5.1.3.14Display the word mapDisplay the reaction diagram Show all sequences 5.1.3.14more role of splice variant GNE1 in basic supply of cells with sialic acids, whereas GNE2 and GNE3 may have a function in finetuning of the sialic acid pathway
Results 1 - 10 of 29 > >>