EC Number   |
Natural Substrates |
|---|
    4.6.1.1 | ATP |
- |
| 4.6.1.1 | ATP |
bifunctional protein harbouring adenylate cyclase and hemolytic activities |
| 4.6.1.1 | ATP |
AC1 is a major adenylyl cyclase isoform controlling cyclic AMP synthesis in the mouse retina, dopamine receptor D4R activation tonically regulates the expression of AC1 in photoreceptors |
| 4.6.1.1 | ATP |
activation of cardiac adenylyl cyclase isozyme ACVI expression increases the function of the failing ischemic heart in mice, overview |
| 4.6.1.1 | ATP |
adenylate cyclase toxin CyaA is responsible for modifications of type 2 alveolar L2 cells from flat to round form in rats after infection, overview. CyaA causes similar morphological changes in various cultured cell lines: EBL, HEK293T, MC3T3-E1, NIH 3T3, and Vero cells are rounded by the toxin, whereas Caco-2, Eph4, and MDCK cells are not. CyaA may also affect tissue cells such as respiratory epithelial cells and may be involved in the pathogenesis of the bacterial infection |
| 4.6.1.1 | ATP |
adenylate cyclase-activating polypeptide type 1 receptor, PAC1-R, is involved in cAMP signalling in the pituitary gland |
| 4.6.1.1 | ATP |
brains from suicide subjects show abnormalities in the cAMP signaling cascade compared to healthy subjects |
| 4.6.1.1 | ATP |
Ca2+-dependent adenylyl cyclases play a specific role in recovery from adaptive presynaptic silencing, involvement of the cAMP pathway in the basal balance between silenced and active synapses, as well as the recovery of baseline function after depolarization-induced presynaptic silencing, e.g. by glutamate, although isozymes AC1 and AC8 are not crucial for the baseline balance between silent and active synapses, overview |
| 4.6.1.1 | ATP |
Ca2+-dependent adenylyl cyclases play a specific role in recovery from adaptive presynaptic silencing, involvement of the cAMP pathway in the basal balance between silenced and active synapses, as well as the recovery of baseline function after depolarization-induced presynaptic silencing, e.g. by glutamate, although isozymes AC1 and AC8 are not crucial for the baseline balance between silent and active synapses, overview. But AC8 plays a particularly important role in rapidly resetting the balance of active to silent synapses after adaptation to strong activity |
| 4.6.1.1 | ATP |
cAMP signaling pathway mediates the activation of exocytosis in sporozoites, overview |
