EC Number   |
Natural Substrates |
|---|
   4.2.3.19 | copalyl diphosphate |
- |
| 4.2.3.19 | ent-copalyl diphosphate |
- |
| 4.2.3.19 | ent-copalyl diphosphate |
involved in biosynthesis of gibberellins |
| 4.2.3.19 | ent-copalyl diphosphate |
second step in plant hormone gibberellin biosynthesis, regulation of the gibberellin biosynthesis, the KS is not rate-determining, overview |
| 4.2.3.19 | ent-copalyl diphosphate |
the enzyme is involved in gibberellin metabolism and biosynthesis of diterpene phytoalexins, overview |
| 4.2.3.19 | ent-copalyl diphosphate |
ent-copalyl diphosphate is converted in an ionization-initiated (class I) reaction that involves formation of a pimarenyl carbocation intermediate, followed by secondary cyclization to a beyeranyl cation which undergoes ring rearrangement and deprotonation to form the tetracyclic ent-kaurene |
| 4.2.3.19 | ent-copalyl diphosphate + H2O |
- |
| 4.2.3.19 | more |
the enzyme prefers normal and syn-copalyl diphosphate over ent-copalyl diphosphate |
| 4.2.3.19 | more |
the bifunctional diterpene synthase PpCPS/KS catalyzes both the reactions of ent-copalyl diphosphate synthase, EC 5.5.1.13, and ent-kaurene synthase. Enzyme CPS produces the precursor for several different diterpenes formed by ent-kaurene synthase, i.e. ent-beyerene, ent-sandaracopimaradiene, ent-kaur-15-ene, ent-kaur-16-ene, and 16-hydroxy-ent-kaurene, via three carbocation intermediates, mechanism, overview. PpCPS/KS is a multiproduct enzyme |
| 4.2.3.19 | syn-copalyl diphosphate |
- |
