EC Number   |
Natural Substrates |
|---|
   4.2.3.13 | (2E,6E)-farnesyl diphosphate |
- |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
- |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
transcription of cad1-C is activated in stems treated with Verticillium dahliae |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
the fungal-elicited production of a (+)-delta-cadinene synthase is consistent with a role for this enzyme as the first committed step in the pathways leading to the related phytoalexins gossypol and lacinilene C in cotton |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
the first step enzyme in the conversion of farnesyl diphosphate to sesquiterpene phytoalexins. The reaction is induced by the infection of cotton with Verticillium dahliae |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
amount of enzyme does not increase significantly in stems treated with Verticillium dahliae due to a high basal level of enzyme in untreated stems |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
the sesquiterpenoid (+)-alpha-cadinene is an intermediate in phytoalexin biosynthesis |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
the product (+)-delta-cadinene is metabolically converted to deoxyhemigossypol, deoxyhemigossypol 6-methyl ether, hemigossypol and hemigossypol 6-methyl ether |
| 4.2.3.13 | 2-trans,6-trans-farnesyl diphosphate |
the enzyme is encoded by a complex gene family that based on homology can be divided into two subfamilies, cad1-A and cad1-C |
| 4.2.3.13 | more |
delta-cadinene synthase is a sesquiterpene cyclase that utilises the universal achiral precursor farnesyl diphosphate (FDP) to generate predominantly the bicyclic sesquiterpene delta-cadinene and about 2% germacradien-4-ol |
