EC Number |
Natural Substrates |
---|
4.2.3.124 | D-glucose 6-phosphate |
- |
4.2.3.124 | D-glucose 6-phosphate |
carbocycle formation |
4.2.3.124 | D-glucose 6-phosphate |
intramolecular carbocyclization |
4.2.3.124 | D-glucose 6-phosphate |
intramolecular carbocyclization, mechanism, overview |
4.2.3.124 | D-glucose 6-phosphate |
intramolecular carbocyclization, multistep process |
4.2.3.124 | D-glucose 6-phosphate |
multistep reaction |
4.2.3.124 | D-glucose 6-phosphate |
the enzyme converts ubiquitous D-glucose 6-phosphate into the specific carbocycle, 2-deoxy-scyllo-inosose with an aid of NAD+-NADH recycling |
4.2.3.124 | more |
the hydroxy group at C-4 is essential for enzyme activity, while the hydroxy groups at C-2 and C-3 are significant for efficial transformation of natural glucose 6-phosphate, but not essential for the reaction catalysis at the active site of enzyme, no activity with 4-deoxy-glucose 6-phosphate, substrate specificity, overview |