EC Number   |
Natural Substrates |
|---|
    4.1.1.5 | (2R)-2-hydroxy-2-methyl-3-oxobutanoate |
- |
| 4.1.1.5 | (2S)-2-hydroxy-2-methyl-3-oxobutanoate |
- |
| 4.1.1.5 | (2S)-2-hydroxy-2-methyl-3-oxobutanoate |
best substrate |
| 4.1.1.5 | (2S)-2-hydroxy-2-methyl-3-oxobutanoate |
acetolactate decarboxylase catalyzes the conversion of both enantiomers of acetolactate to the (R)-enantiomer of acetoin, via a mechanism that involves a prior rearrangement of the non-natural (R)-enantiomer substrate to the natural (S)-enantiomer |
| 4.1.1.5 | (S)-2-hydroxy-2-methyl-3-oxobutanoate |
- |
| 4.1.1.5 | (S)-2-hydroxy-2-methyl-3-oxobutanoate |
alpha-acetolactate metabolism |
| 4.1.1.5 | (S)-2-hydroxy-2-methyl-3-oxobutanoate |
catalyzes the second step of the acetoin pathway, catabolism of pyruvate, responsible for the regulation of the pool of alpha-acetolactate in the cell during branched-chain amino acids metabolism, mode of transcriptional and translational regulation of ALDC production |
| 4.1.1.5 | (S)-2-hydroxy-2-methyl-3-oxobutanoate |
regulates leucine and valine biosynthesis by diverting the flux of alpha-acetolactate towards acetoin when branched-chain amino acids are present at a high concentration, involved in catabolism of pyruvate to acetoin, but less important function in vivo |
| 4.1.1.5 | 2-Hydroxy-2-methyl-3-oxobutanoate |
enzyme is a key regulator of Val and Leu biosynthesis, by controlling the acetolactate flux by a shift to catabolism |
| 4.1.1.5 | 2-Hydroxy-2-methyl-3-oxobutanoate |
enzyme catalyzes the second step of the 2,3-butanediol pathway |
