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Results 1 - 3 of 3

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.6.1.39	dTTP + H2O	-
3.6.1.39	dTTP + H2O	mechanisms of DNA-dependent and-independent dTTP hydrolysis by the gene 4 protein of bacteriophage T7 differ in the pathways by which these reactions are catalyzed. In the presence of dTTP, gene 4 protein monomers assemble as a ring that binds single-stranded DNA and couples the hydrolysis of dTTP to unidirectional translocation and the unwinding of duplex DNA, overview
3.6.1.39	dTTP + H2O	dTTP hydrolysis is coupled to DNA unwinding, dependence of dTTP hydrolysis rates on dsDNA stability, the force-producing step during DNA unwinding is not associated with dTTP binding, but dTTP hydrolysis or phosphate release

Results 1 - 3 of 3

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Release 2023.1 (January 2023)