EC Number |
Natural Substrates |
---|
3.6.1.23 | dCTP + H2O |
- |
3.6.1.23 | dUTP + H2O |
- |
3.6.1.23 | dUTP + H2O |
removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA |
3.6.1.23 | dUTP + H2O |
removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, essential for replication and cell survival |
3.6.1.23 | dUTP + H2O |
removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, provides substrate for dTTP synthesis |
3.6.1.23 | dUTP + H2O |
removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA, provides the substrate thymidylate synthase and is therefore essential for the synthesis of dTTP |
3.6.1.23 | dUTP + H2O |
biological roles and functions of dUTPase-related proteins and domains, overview |
3.6.1.23 | dUTP + H2O |
dUMP is required for biosynthesis of dTTP, overview |
3.6.1.23 | dUTP + H2O |
the enzyme is essential in the lytic cycle of the virus |
3.6.1.23 | dUTP + H2O |
the enzyme prevents incorporation of uracil into DNA by strict regulation of the cellular dUTP to dTTP ratio, developmental regulation of the isozymes at mRNA and protein levels |