EC Number   |
Natural Substrates |
|---|
    3.5.4.9 | 10-formyltetrahydrofolate |
- |
| 3.5.4.9 | 5,10-methenyl-tetrahydrofolate + H2O |
trifunctional enzyme exhibits synthetase, dehydrogenase and cyclohydrolase activities |
| 3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O |
- |
| 3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O |
bifunctional enzyme exhibits dihydrogenase and cyclohydrolase activities |
| 3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O |
trifunctional enzyme exhibits synthetase, dehydrogenase and cyclohydrolase activities |
| 3.5.4.9 | 5,10-methenyltetrahydrofolate + H2O |
cyclodehydrolase activity of MTHFD1 |
| 3.5.4.9 | more |
the determined amount of 5-formyltetrahydrofolate formation in the liver is low, possible role in one-carbon metabolism |
| 3.5.4.9 | more |
enzyme deficiency by G1958A polymorphism is involved in spontaneous cervical artery dissections |
| 3.5.4.9 | more |
dehydrogenase and cyclohydrogenase activities are contained in the single bifunctional protein DHCH1 |
| 3.5.4.9 | more |
MTHFD1 is a trifunctional enzyme that interconverts tetrahydrofolate derivatives for nucleotide synthesis |
