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Results 1 - 10 of 25 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7Collagen + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7collagen I + H2O degradation
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7collagen III + H2O degradation
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7Collagen type I + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7Collagen type III + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7Collagen type III + H2O ability of MMP-1 to unwind triple-helical collagen
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7more ligation of keratinocyte alpha2beta1 integrin by type 1 collagen induces expression of matrix metalloproteinase-1. The MMP-1 activity is required for the alpha2beta1 integrin-dependent migration of primary keratinocytes across collagenous matrices. MMP-1 binds to the I domain of the alpha2 intergrin subunit
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7more matrix metalloproteinase 1 interacts with neuronal integrins and stimulates dephosphorylation of Akt and neuronal death through a non-proteolytic mechanism. MMP-1 might contribute to the neuronal damage which occurs in association with degenerative and inflammatpry conditions characterized by elevated levels of this proteinase
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7more MMP-1 is involved in intestinal re-epithelization in vivo and is upregulated by cytokines relevant in wound repair
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.7more enzyme regulation on expression and protein levels, overview
Results 1 - 10 of 25 > >>