EC Number |
Natural Substrates |
---|
3.4.24.40 | Fibrin + H2O |
- |
3.4.24.40 | Fibrinogen + H2O |
the enzyme hydrolyzes the Aalpha chain in 1 min, the Bbeta chain in 5 min, and the gamma chain in more than 1 h |
3.4.24.40 | human complement component C1 + H2O |
- |
3.4.24.40 | human complement component C2 + H2O |
- |
3.4.24.40 | more |
important factor in virulence seen in several microbial diseases caused by Pseudomonas aeruginosa and Serratia marcescens, e.g. corneal ulcers and pneumonia, inducible enzyme |
3.4.24.40 | more |
inhibits cytokine-induced signaling in A549 pulmonary epithelial cells |
3.4.24.40 | more |
inhibits IFN-gamma antiviral and immunomodulatory activity |
3.4.24.40 | more |
the enzyme does not degrade urokinase, streptokinase, and tissue plasminogen activator |