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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.23.B3
EIAV Gag-Pol polypetide + H2O
several cleavage sites
3.4.23.B3
EIAV nucleocapsid protein + H2O
processing in the early phase of virus replication
3.4.23.B3
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the enzyme is essential for processing gag and gal-pol polyproteins in order to generate new infectious viral particles
3.4.23.B3
more
the enzyme processes viral polyproteins into functional molecules during replication and it also cleaves viral nucleocapsid protein during infection
3.4.23.B3
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the retropepsin is expressed as part of the Gag-Pol polyprotein precursor, the enzyme cleaves the precursor into functional proteins during or after assembly and budding of the virions, thereby releasing itself
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