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EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.23.B2	Pr55Gag polyprotein + H2O	lentiviral Gag polyprotein, proteolytic processing for activation, cleavage in the late stages of life cycle, required for maturation of the virion meaning a structural rearrangement required for infectivity in budding virions, cleavage in the phosphorylated capsid domains, the enzyme is not influenced by the preceeding phosphorylation, but cleaved sites are no longer phosphorylated, while incompletely cleaved capsid domains are phosphorylated to a greater extent, overview

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Release 2023.1 (January 2023)