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Results 1 - 10 of 21 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64cationic channel subunit transient receptor potential channel 1 + H2O i.e. TRPC1, plays a role in regulating innate immunity by modulating channel complexes during inflammatory responses
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64gasdermin D + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more overexpression induces apoptosis
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more phenotype of animals deficient in caspase-11: resistant to lipopolysaccharide-induced caspase-1 processing, interleukin-1alpha and interleukin-beta secretion, and endotoxic shock
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more the enzyme is a critical initiator caspase responsible for the activation of caspase-3. The enzyme is an upstream activator of caspase-1. Caspase-11 deficient animals have a reduced number of apoptotic cells and a defect in caspase-3 activation after middle cerebral artery occlusion. The enzyme is A VERY IMPORTANT REGULATOR OF APOPTOSIS
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more enzyme is involved in cytokine activation
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more pro-caspase-11 physically interacts with pro-ICE in cells, the expression of casp-11 is essential for activation of ICE. Caspase-11 is a compinent of ICE complex and is required for the activation of ICE. Important role of ICE and caspase-11 in mediating apoptosis in pathological conditions
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more the enzyme may play a very important role in apoptosis and inflammatory responses and may be an upstream regulator of ICE
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64more the enzyme is involved in cytokine activation
Results 1 - 10 of 21 > >>