EC Number   |
Natural Substrates |
|---|
   3.4.22.43 | Elastin + H2O |
- |
| 3.4.22.43 | Elastin + H2O |
elastin degradation activity leading to loss of elasticity in atherosclerosis |
| 3.4.22.43 | Gelatin + H2O |
- |
| 3.4.22.43 | more |
the corneal enzyme stays within cells and is not secreted, suggesting that components of the corneal epithelium are likely substrates |
| 3.4.22.43 | more |
the predominant expression in thymus suggests a role in the immune system, the expression in testes suggests a role in fertilization processes, the expression in cancer cells together with its absence in normal cells suggests a role in tumor processes |
| 3.4.22.43 | more |
the enzyme and inhibitor cystatin M/E are involved in regulation of epidermal differentiation |
| 3.4.22.43 | more |
the enzyme can stimulate H2O2 production, enzyme expression is increased in keratoconus corneas compared to healthy ones, oxidative stress might be involved in the disorder |
| 3.4.22.43 | more |
direct interaction of cathepsin V with TLR4 and its adaptor protein MyD88 |
| 3.4.22.43 | neuropeptide Y + H2O |
- |
| 3.4.22.43 | plasminogen + H2O |
- |
