EC Number   |
Natural Substrates |
|---|
   3.4.22.34 | 11S proglobulin + H2O |
processing to the active trimer |
| 3.4.22.34 | acetoacetyl-CoA synthetase + H2O |
Asn547 is the specific cleavage site of acetoacetyl-CoA synthetase in mouse livers. The cleaved form of acetoacetyl-CoA synthetase (1-547) loses the ability to convert acetoacetate to acetoacetyl-CoA. Cleavage of acetoacetyl-CoA synthetase by legumain is critical for the regulation of enzymatic activity and results in gain-of-function changes. Acetoacetyl-CoA synthetase(1-547) increases the protein expression of caveolin-1, the principal component of the caveolae |
| 3.4.22.34 | annexin II + H2O |
cleavage of the N-terminus, enzyme plays a role in inactivation and degradation of annexin II in endosomes and lysosomes |
| 3.4.22.34 | bovine albumin + H2O |
- |
| 3.4.22.34 | bovine haemoglobin + H2O |
exhibited strict specificity for the asparaginyl bonds on the carboxy-terminal side of a peptide |
| 3.4.22.34 | cathepsin L + H2O |
processing/activation |
| 3.4.22.34 | cystatin E + H2O |
- |
| 3.4.22.34 | Hemoglobin + H2O |
the enzyme is involved in host hemoglobin degradation |
| 3.4.22.34 | more |
processing enzyme of vacuoles, is responsible for the conversion of several vacuolar precursors into their mature forms |
| 3.4.22.34 | more |
thought to be involved in the hydrolysis of stored seed proteins |
