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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.21.B4
more
can trigger DNA fragmentation and is involved in apoptosis
3.4.21.B4
more
granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice. GrzK plays an important role in CD8+ T-cell cytotoxicity both in the presence and absence of grzA and B
3.4.21.B4
Protein + H2O
-
3.4.21.B4
redox factor-1/apurinic apyrimidinic endonuclease Ape1 + H2O
Ape1 cleavage by Granzyme K facilitates intracellular reactive oxygen species accumulation and enhances granzyme K-induced cell death
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