EC Number   |
Natural Substrates |
|---|
   3.4.17.8 | more |
the enzyme is involved in cell wall synthesis, the cell wall forming pentapeptide unit of Staphylococcus sciuri consists of a D-alanine and for glycine residues |
| 3.4.17.8 | more |
activation of the L,D-transpeptidation pathway can also release inhibition of transglycosylation, leading to cross-resistance to glycopeptides and beta-lactams following extensive hydrolysis of D-Ala5 from the cytoplasmic precursor UDP-MurNAc-pentapeptide by a D,D-carboxypeptidase, mechanism of glycopeptide resistance, overview |
| 3.4.17.8 | more |
PBP5 performs a DD-carboxypeptidase reaction on the bacterial peptidoglycan, the major constituent of the cell wall |
| 3.4.17.8 | more |
the enzyme is involved in cell wall formation, overview |
| 3.4.17.8 | UDP-MurNAc-pentapeptide + H2O |
i.e. UDP-acetylmuramic acid-L-Ala-D-iGlu-L-Lys-D-Ala-D-Ala |
| 3.4.17.8 | UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + H2O |
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