EC Number   |
Natural Substrates |
|---|
   3.4.17.10 | more |
- |
| 3.4.17.10 | more |
C-terminal histidine is removed at a very slow rate |
| 3.4.17.10 | more |
conversion of peptide hormone precursor into their smaller active forms |
| 3.4.17.10 | more |
biosynthesis of insulin in pancreatic beta-cells |
| 3.4.17.10 | more |
highly specific for C-terminal basic amino acids Arg in decreasing order: Arg, Lys, His, does not cleave other amino acids |
| 3.4.17.10 | more |
releases C-terminal arginine or lysine residues from the hexapeptide precursor of [Met]enkephalin and [Leu]enkephalin, forming the pentapeptide enkephalin, associated with the biosynthesis of many peptide neurotransmitters and hormones |
| 3.4.17.10 | more |
the enzyme is a sorting receptor for the regulated secretory pathway. The sorting receptor function of the enzyme necessitates its interaction with glycosphingolipid-cholesterol rafts at the trans-Golgi network, thereby anchoring it in position to bind to its prohormone cargo |
| 3.4.17.10 | more |
the enzyme is a sorting receptor that directs the prohormone pro-opiomelanocortin to the regulated secretory pathway and is also a prohormone processing enzyme in neuro/endocrine cells |
| 3.4.17.10 | more |
altered biosynthesis of the neuropeptide processing enzyme after brain ischemia: molecular mechanism and implication |
| 3.4.17.10 | more |
carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina |
