Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Natural Substrates/ Products (Substrates)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 10 of 32 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1amyloid beta-peptide(1-40) + H2O cleavage at the Asp7-Ser9 bond. Compared with amyloid beta-peptide(1-40), aggregation and cytotoxic effects of the degradation products amyloid beta-peptide(1-7) and amyloid beta-peptide(8-40) are reduced ot virtually absent. The enzyme inhibits aggregation, deposition, and cytotoxicity of amyloid beta-peptide in vitro may affect susceptibility to Alzheimer‘s disease
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1amyloid beta-protein 1-40 + H2O ACE cleaves amyloid beta-protein 1-40 between Asp7 and Ser8
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1amyloid beta-protein 1-42 + H2O angiotensin-converting enzyme converts amyloid beta-protein 1-42 to amyloid beta-protein1-40. ACE regulates Abeta1-42/Abeta1-40 ratio in vivo by converting secreted Abeta1-42 to Abeta1-40 and degrading Abetas.The upregulation of ACE activity can be a novel therapeutic strategy for Alzheimer’s disease
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1amyloid beta-protein 1-42 + H2O angiotensin-converting enzyme converts amyloid beta-protein1-42 to amyloid beta-protein1-40. ACE regulates Abeta1-42/Abeta1-40 ratio in vivo by converting secreted Abeta1-42 to Abeta1-40 and degrading Abetas. The upregulation of ACE activity can be a novel therapeutic strategy for Alzheimer’s disease
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1amyloid beta-protein 1-42 + H2O ACE cleaves amyloid beta-protein 1-42 at multiple sites
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1angiotensin I + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1angiotensin I + H2O enzyme plays a major role in blood pressure regulation
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1angiotensin I + H2O the enzyme plays an important role in blood pressure homeostasis
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1angiotensin I + H2O angiotensin II is a vasoconstrictor that raises blood pressure and is formed from angiotensin I by the angiotensin I converting enzyme in the reninangiotensin system
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1angiotensin I + H2O i.e. DRVYIHPFHL
Results 1 - 10 of 32 > >>