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EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.14.12	more	the production of prolyl tripeptidyl peptidase may contribute to the pathogenesis of periodontal tissue destruction though the mutual interaction of this enzyme, host and bacterial collagenases, and dipeptidyl peptidases in the degradation of collagen during the course of infection
3.4.14.12	more	the enzyme releases a tripeptide, X-X-P, from substrates exposing of a free N-terminus and a proline residue in the third position

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Release 2023.1 (January 2023)