EC Number   |
Natural Substrates |
|---|
   3.4.11.21 | angiotensin + H2O |
- |
| 3.4.11.21 | angiotensin + H2O |
intracellular protein and peptide metabolism |
| 3.4.11.21 | angiotensin + H2O |
metabolism of angiotensin I, angiotensin II, cholecystokinin-8 and neuropeptide, solube and membrane-bound AspAP play different functional roles in the brain |
| 3.4.11.21 | angiotensin II + H2O |
aspartyl aminopeptidase and several other aminopeptidases, i.e. angiotensinases, are involved in angiotensin II and cholecystokinin, CCK, metabolism, angiotensin II is the principal effector of the renin-angiotensin-system, RAS, which induces vasoconstriction and increases sodium and water retention thereby leading to increased blood pressure |
| 3.4.11.21 | Asp-Xaa + H2O |
- |
| 3.4.11.21 | aspartyl peptides + H2O |
activation and degradation of several neuropeptides, excitatory Asp and Glu implicated in pathogenesis of different neurogeneratives diseases |
| 3.4.11.21 | aspartyl peptides + H2O |
catabolism of intracellular proteins, breakdown of abnormal cell proteins, supplement of nutritional sources |
