EC Number   |
Natural Substrates |
|---|
   3.2.2.21 | alkylated DNA + H2O |
- |
| 3.2.2.21 | alkylated DNA + H2O |
cellular repair of alkylated DNA base modifications |
| 3.2.2.21 | alkylated DNA + H2O |
DNA repair enzyme, inducible base excision repair pathway of DNA alkylation damage |
| 3.2.2.21 | alkylated DNA + H2O |
induced by cell exposure to sublethal doses of alkylating agents, important role in the excision of base damage from single-stranded regions transiently formed in DNA during transcription and replication |
| 3.2.2.21 | alkylated DNA + H2O |
short-patch base excision repair pathway, repair of alkylation and oxidative DNA damage |
| 3.2.2.21 | alkylated DNA + H2O |
binds mismatch base-pairs in DNA |
| 3.2.2.21 | alkylated DNA + H2O |
inducible pathway for repair of DNA damaged by simple alkylating agents such as methylmethanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine |
| 3.2.2.21 | more |
AlkD is involved exclusively in the repair of alkylation damage |
| 3.2.2.21 | more |
enzyme is involved in DNA excision repair |
| 3.2.2.21 | more |
the enzyme is induced in response to DNA alkylation, and it protects cells from alkylated nucleobases by catalyzing their excision |
