EC Number   |
Natural Substrates |
|---|
   3.1.6.2 | cholesterol sulfate + H2O |
cholesterol sulfate metabolism, steroid sulfohydrolase pathway |
| 3.1.6.2 | dehydroepiandrosterone 3-sulfate + H2O |
in adipose tissue, further concersion to bioactive androgens and estrogens |
| 3.1.6.2 | dehydroepiandrosterone sulfate + H2O |
- |
| 3.1.6.2 | dehydroepiandrosterone sulfate + H2O |
androgen metabolism, dehydroepiandrosterone sulfate may play a part in the pathogenesis of androgenic alopecia |
| 3.1.6.2 | dehydroepiandrosterone sulfate + H2O |
hydrolyzes dehydroepiandrosterone sulfate to its active, unsulfated form |
| 3.1.6.2 | dehydroepiandrosterone sulfate + H2O |
oestrogen biosynthesis |
| 3.1.6.2 | dehydroepiandrosterone sulfate + H2O |
dehydroepiandrosterone is reduced to a diol by 17beta-HSD1, apart from estrone, the steroid sulfatase pathway is also responsible for the production of another steroid with estrogenic properties, namely androstenediol |
| 3.1.6.2 | estrone 3-sulfate + H2O |
hydrolyzes estrone 3-sulfate to its active, unsulfated form |
| 3.1.6.2 | estrone sulfate |
- |
| 3.1.6.2 | estrone sulfate + H2O |
- |
