EC Number   |
Natural Substrates |
|---|
   3.1.4.52 | 3',5'-di-cGMP + H2O |
- |
| 3.1.4.52 | 5'-phosphoguanylyl-(3'->5')guanosine + H2O |
- |
| 3.1.4.52 | c-di-GMP + H2O |
- |
| 3.1.4.52 | cyclic di-3',5'-guanylate + H2O |
- |
| 3.1.4.52 | cyclic di-3',5'-guanylate + H2O |
degradation |
| 3.1.4.52 | cyclic di-3',5'-guanylate + H2O |
RocR, an EAL domain protein that regulates the expression of virulence genes and biofilm formation in Pseudomonas aeruginosa PAO1, catalyzes the hydrolysis of cyclic di-GMP by using a general base-catalyzed mechanism with the assistance of Mg2+ ion |
| 3.1.4.52 | cyclic di-3',5'-guanylate + H2O |
BB0374/PdeB specifically hydrolyzed cyclic di-GMP |
| 3.1.4.52 | more |
CdgC regulates expression of genes required for Vibrio cholerae polysaccharide synthesis and the transcriptional regulator genes vpsR, vpsT, and hapR. CdgC also regulates expression of genes involved in extracellular protein secretion, flagellar biosynthesis, and virulence factor production. The regulons of CdgC and MbaA overlap, but with different timing |
| 3.1.4.52 | more |
enzyme and cyclic guanylate cyclase YvvD a may be part of a fine-tuning mechanism for regulating the intracellular levels of cyclic diguanylate |
| 3.1.4.52 | more |
enzyme plays a protective role in response to oxidative stress |
