EC Number   |
Natural Substrates |
|---|
   3.1.4.41 | 2-lysophosphatidylcholine + H2O |
- |
| 3.1.4.41 | lysophosphatidylcholine + H2O |
- |
| 3.1.4.41 | more |
enzyme induces serotonin secretion |
| 3.1.4.41 | more |
sphingomyelin of the red cell membrane is hydrolyzed by a sphingomyelinase D-type activity expressed by venom hemolysin |
| 3.1.4.41 | more |
enzyme is a poisonous toxin which induces platelet aggregation |
| 3.1.4.41 | more |
Corynebacterium ovis toxin is a phospholipase D which attacks the sphingomyelin of endothelial cells of blood vessels |
| 3.1.4.41 | more |
physiological effects of enzyme |
| 3.1.4.41 | more |
enzyme induces necrotic lesions in rabbits |
| 3.1.4.41 | more |
SMaseD induces apoptosis in human keratinocytes, which is associated with an increased expression of metalloproteinase-2 and -9 |
| 3.1.4.41 | more |
the recombinant protein rLIPLD1 shows hydrolytic activity on sphingomyelin and in vitro hemolytic activity on human red blood cells, whereas rLIPLD2 is inactive |
