EC Number |
Natural Substrates |
---|
3.1.4.39 | 1-alkyl-sn-glycero-3-phosphocholine + H2O |
- |
3.1.4.39 | 1-alkyl-sn-glycero-3-phosphocholine + H2O |
16:0, 18:1 and 18:2-lysophosphatidylcholine are the predominant physiological substrates of the enzyme in rabbit aqueous humor |
3.1.4.39 | 1-alkyl-sn-glycero-3-phosphoethanolamine + H2O |
- |
3.1.4.39 | 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine + H2O |
may play a role in the metabolism of platelet-activating factor |
3.1.4.39 | lysophosphatidyl choline + H2O |
- |
3.1.4.39 | lysophosphatidylcholine + H2O |
- |
3.1.4.39 | lysophosphatidylcholine + H2O |
present in the plasma |
3.1.4.39 | lysophosphatidylcholine + H2O |
lysophospholipase D activity |
3.1.4.39 | more |
the product lysophosphatidic acid mediates multiple biological functions |
3.1.4.39 | more |
activity implicated in a large variety of biological processes (during normal development and under pathological conditions). Developmental roles include adipogenesis, intestinal cell motility and neurite morphology, a contribution to disease is described for alzheimer's disease, chronic hepatitis C, multiple sclerosis, neuropathic pain, obesity, rheumatoid arthritis |