EC Number   |
Natural Substrates |
|---|
   3.1.13.5 | more |
enzyme is involved in structured RNA processing |
| 3.1.13.5 | more |
the enzyme may represent an intracellular scavenging mechanism for denatured tRNAs and other inactive RNA molecules |
| 3.1.13.5 | more |
in vitro, TbRND exhibits 3' to 5' exoribonuclease activity, with specificity toward uridine homopolymers, including the 3' oligo(U) tails of guide RNAs that provide the sequence information for RNA editing |
| 3.1.13.5 | tRNA containing extra residues at the 3'-terminus |
ribonuclease D is not essential for the normal growth of Escherichia coli or bacteriophage T4 or for the biosynthesis of a T4 suppressor tRNA |
| 3.1.13.5 | tRNA containing extra residues at the 3'-terminus |
the enzyme can act at the 3'-terminus of tRNA in vivo. RNase D participates in tRNA metabolism |
