EC Number   |
Natural Substrates |
|---|
   2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
| 2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
does not make active heparan sulfate, transfers sulfate to GlcA2S-GlcNS and IdoA2S-GlcNS |
| 2.8.2.29 | more |
a gD-type-3-OST isozyme is essential for a conserved neurogenic signaling pathway regulated by Notch |
| 2.8.2.29 | more |
heparan sulfate chains contain sulfated domains termed the HS fine structure, which gives HS specific binding affinities for extracellular ligands, heparan sulfate 3-O-sulfotransferases catalyze the transfer of sulfate groups to the 3-O position of glucosamine residues of heparan sulfate, a rare, but essential heparan sulfate chain modification required for HS fine structure |
| 2.8.2.29 | more |
modification of heparan sulfate and the ability of 3-OST-2 to generate receptors for both wild-types and some mutant forms of HSV-1, spreading of receptors mediating cell-to-cell fusion |
