EC Number   |
Natural Substrates |
|---|
   2.8.2.23 | 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate-glucosamine |
regulation of blood coagulation |
| 2.8.2.23 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
| 2.8.2.23 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
3-OST catalyzes a key substitution in heparan sulfate sequences of biological importance, in particular heparan sulfate anticoagulant activity |
| 2.8.2.23 | 3-phosphoadenylylsulfate + heparin-glucosamine |
enzyme brings about the final stage in biosynthesis of heparin |
| 2.8.2.23 | 3-phosphoadenylylsulfate + heparin-glucosamine |
biosynthesis of heparin/heparan sulfate |
| 2.8.2.23 | more |
gD-type-3-OST is essential for a conserved neurogenic signaling pathway regulated by Notch |
| 2.8.2.23 | more |
heparan sulfate chains contain sulfated domains termed the HS fine structure, which gives HS specific binding affinities for extracellular ligands, heparan sulfate 3-O-sulfotransferases catalyze the transfer of sulfate groups to the 3-O position of glucosamine residues of heparan sulfate, a rare, but essential heparan sulfate chain modification required for HS fine structure |
| 2.8.2.23 | more |
HS3ST-2 is a marker for specific subsets of TrkC-expressing cutaneous low-threshold mechanosensory and proprioceptive mechanosensory neurons, overview. HS3ST-2 is involved in formation of sensory endings of nerves in skeletal muscle |
