EC Number |
Natural Substrates |
---|
2.8.2.21 | 3'-phosphoadenylyl sulfate + keratan |
- |
2.8.2.21 | 3'-phosphoadenylyl sulfate + keratan |
keratan sulfate proteoglycan is expressed in the extracellular matrix or cell surface in numerous tissues, predominantly in those of the cornea, cartilage, and brain |
2.8.2.21 | 3'-phosphoadenylyl sulfate + keratan |
pericellular localization of R-10G reactive KS epitopes in perineuronal net-positive neurons in the visual cortex of adult mice |
2.8.2.21 | 3'-phosphoadenylyl sulfate + N-acetyllactosamine |
- |
2.8.2.21 | more |
Gn6ST produces keratan sulfate in cooperation with KSG6ST, inactivation of Gn6ST may lead to macular corneal dystrophy |
2.8.2.21 | more |
sulfation of GlcNAc is coupled to enlongation of keratan sulfate chain |
2.8.2.21 | more |
loss of GST-4beta causes macular corneal dystrophy |
2.8.2.21 | more |
sulfation of GlcNAc residues precedes sulfation of Gal residues during biosynthesis of keratan sulfate |
2.8.2.21 | more |
KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview |