EC Number   |
Natural Substrates |
|---|
    2.7.9.1 | AMP + phosphoenolpyruvate + diphosphate |
- |
| 2.7.9.1 | AMP + phosphoenolpyruvate + diphosphate |
synthesis of ATP is not thermodynamically favorable in trophozoites of Entamoeba histolytica |
| 2.7.9.1 | AMP + phosphoenolpyruvate + diphosphate |
the enzyme likely works in the direction of pyruvate production. PPDK is a central enzyme in the metabolism of glycosome by providing a link between glycolysis fatty acid oxidation and biosynthetic diphosphate-producing pathways. PPDK seems to replace diphosphatase in its classical thermodynamic role of displacing the equilibrium of diphosphate-producing reactions, as well as in its role of eliminating the toxic diphosphate |
| 2.7.9.1 | AMP + phosphoenolpyruvate + diphosphate |
the Opaque-2 gene has regulatory function in metabolic pathways, mutation of Opaque-2 affects PPDK activity, overview |
| 2.7.9.1 | AMP + phosphoenolpyruvate + diphosphate |
the enzyme is dependent on AMP in the phosphotransfer networks |
| 2.7.9.1 | ATP + pyruvate + phosphate |
- |
| 2.7.9.1 | ATP + pyruvate + phosphate |
activity strictly and reversibly regulated by light |
| 2.7.9.1 | ATP + pyruvate + phosphate |
permits the incorporation of pyruvate into carbohydrates in the light in Crassulacean acid metabolism |
| 2.7.9.1 | ATP + pyruvate + phosphate |
the enzyme enables the organism to conserve the energy residing in the diphosphate resulting from protein and glycogen synthesis |
| 2.7.9.1 | ATP + pyruvate + phosphate |
enzyme activity has implication in the regulation of gluconeogenesis and carbohydrate oxidation |
