EC Number   |
Natural Substrates |
|---|
   2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
- |
| 2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways |
| 2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
phosphorylation of isocitrate dehydrogenase during growth on acetate is to render this enzyme rate-limiting in the citric acid cycle, this should cause an increase in the level of isocitrate and divert the flux of carbon through the glyoxylate bypass |
| 2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
controls the oxidative metabolism, exibits a high intrinsic ATPase activity |
| 2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
Escherichia coli AceK can cross-phosphorylate Burkholderia pseudomallei IDH |
| 2.7.11.5 | ATP + [isocitrate dehydrogenase (NADP+)] |
isocitrate dehydrogenase kinase/phosphatase (AceK) is a bifunctional enzyme with both kinase and phosphatase activities |
| 2.7.11.5 | more |
AceK is a bifunctional enzyme, that phosphorylates and dephosphorylates isocitrate dehydrogenase with its unique active site that harbours both the kinase and ATP/ADP-dependent phosphatase activities |
