EC Number |
Natural Substrates |
---|
2.7.11.31 | ATP + acetyl-CoA carboxylase |
- |
2.7.11.31 | ATP + acetyl-CoA carboxylase |
the enzyme is involved in the regulation of hepatic lipids via its downstream effector acetyl-CoA carboxylase, enzyme inhibition leads to an increased level of triacylglycerols and accumulation of lipids, metformin decreases lipid accumulation, induced by high D-glucose levels, by activating the enzyme, the enzyme functions as energy intracellular sensor |
2.7.11.31 | ATP + acetyl-CoA carboxylase 1 |
- |
2.7.11.31 | ATP + ATF1 |
important reaction in enhancement of transcriptional activity |
2.7.11.31 | ATP + ATF2 |
- |
2.7.11.31 | ATP + CREB |
important reaction in enhancement of transcriptional activity |
2.7.11.31 | ATP + CREB1 |
AMPK competes with protein kinase A for the Ser119 phosphorylation site |
2.7.11.31 | ATP + CREBL2 |
- |
2.7.11.31 | ATP + CREM |
important reaction in enhancement of transcriptional activity |
2.7.11.31 | ATP + eukaryotic elongation factor 2 kinase |
phosphorylation at Ser398, the enzyme plays a regulatory role in eEF2 kinase activity, overview |