EC Number   |
Natural Substrates |
|---|
   2.7.11.13 | ATP + a protein |
- |
| 2.7.11.13 | ATP + Akt |
phosphorylation by PKC isozymes at Ser473, regulation of the phosphorylation activity by PKCbetaII in mast cells stimulated by stem cell factor or interaleukin-3, and in serum-stimulated fibroblasts, and in antigen-receptor stimulated T- or B-lymphocytes, overview |
| 2.7.11.13 | ATP + beta-catenin |
- |
| 2.7.11.13 | ATP + Btk |
specific phosphorylation leads to inhibition of Btk membrane translocation and activation and the downstream events that promote PKCbeta activation, mechanism, overview |
| 2.7.11.13 | ATP + calcium-independent phospholipase A2 |
PKC regulates membrane-associated, calcium-independent phospholipase A2 in coronary artery endothelial cells in competition to thrombin, overview |
| 2.7.11.13 | ATP + casein kinase 1delta |
phosphorylation at Ser328, Thr329, and Ser370 |
| 2.7.11.13 | ATP + CTP:phosphoethanolamine cytidylyltransferase |
phosphorylation at Ser215 and Ser223 |
| 2.7.11.13 | ATP + diacylglycerol kinase-zeta |
the enzyme, especially isozyme PKCalpha, inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein |
| 2.7.11.13 | ATP + endothelial nitric oxide synthase |
the enzyme is responsible for the negative regulation of endothelial nitric oxide synthase, a key enzyme in nitric oxide-mediated signal transduction, phosphorylation reduces the affinity of nitric oxide synthase for calmodulin |
| 2.7.11.13 | ATP + histone H1-IIIS |
isozyme PKCbeta |
