EC Number |
Natural Substrates |
---|
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-triphosphate |
- |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
- |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
regulatory mechanism of isoenzyme B involving phosphorylation by both protein kinase C and CaM kinase II |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
differential expression and regulation of the two enzyme isoforms A and B provides multiple mechanisms for regulating the cytosolic level of inositol 1,4,5-trisphosphate in cells, regulation mechanisms |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate have separate second messenger roles, perhaps both relating to Ca2+-signaling events |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
inositol 1,4,5-trisphosphate is a second messenger |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
important alternative route for inositol 1,4,5-trisphosphate metabolism in skeletal muscle |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
phosphorylation of IP3 in dentritic spines to produce IP4 is important for modulating the compartmentalization of calcium at synapses, control of calcium signals, the rapid, localized synthesis of IP4 may have complex effects on cytosolic calcium and on the molecular mechanisms that control learning and memory |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
IP3K regulates the intracellular level of the 2 second messengers Ins(1,4,5)P3 and Ins(1,3,4,5)P4 |
2.7.1.127 | ATP + 1D-myo-inositol 1,4,5-trisphosphate |
target enzyme of cellular regulation, enzyme controls the rate of InsP3 metabolism |