EC Number |
Natural Substrates |
---|
2.4.2.28 | 5'-deoxy-5'-(hydroxyethylthio)adenosine + phosphate |
trypanocidal substrate analogue |
2.4.2.28 | 5'-deoxy-5'-(hydroxyethylthio)adenosine + phosphate |
preincubation of cells with the substrate lead to 22-37% inhibition of spermidine synthesis from ornithine and 2-7fold increased cytosolic levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine, and up to 8fold increased cytosolic level of 5'-methyladenosine |
2.4.2.28 | 5'-deoxy-5'-methylthioadenosine + phosphate |
salvage reaction |
2.4.2.28 | 5'-deoxy-5'-methylthioadenosine + phosphate |
involved in cardiac purine breakdown during ischemia |
2.4.2.28 | 5'-deoxy-5'-methylthioadenosine + phosphate |
substrate is a by-product of polyamine biosynthesis, which is essential for cell growth and proliferation |
2.4.2.28 | 5'-deoxy-5'-methylthioadenosine + phosphate |
- |
2.4.2.28 | 5'-methylthioadenosine + phosphate |
- |
2.4.2.28 | 5'-methylthioadenosine + phosphate |
important for the salvage of adenine and methionine |
2.4.2.28 | 5'-methylthioadenosine + phosphate |
an antiproliferative effect on stimulated human lymphocytes and virally transformed mouse fibroblasts |
2.4.2.28 | 5'-methylthioadenosine + phosphate |
involved in salvage of adenine and methionine from 5'-methylthioadenosine |