EC Number |
Natural Substrates |
---|
2.4.1.17 | 11alpha-hydroxyprogesterone + UDP-glucuronate |
- |
2.4.1.17 | 16alpha-hydroxyprogesterone + UDP-glucuronate |
UGT2B15 and UGT2B17 are the major enzyme forms involved in the high-affinity component of 16alpha-hydroxyprogesterone glucuronidation |
2.4.1.17 | 16alpha-hydroxyprogesterone + UDP-glucuronate |
- |
2.4.1.17 | 2 UDP-D-glucuronate + 2 dexmedetomidine |
the major metabolic pathway of dexmedetomidine, i.e. (4S)-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, in humans is N-glucuronidation at the imidazolate nitrogens to N3- and N1-glucuronides |
2.4.1.17 | 2 UDP-D-glucuronate + 2 levomedetomidine |
the major metabolic pathway of levomedetomidine, i.e. (4R)-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, in humans is N-glucuronidation at the imidazolate nitrogens to N3-glucuronide |
2.4.1.17 | 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid + UDP-glucuronate |
glucuronidation of 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid is mainly catalyzed by UGT1A1, UGT1A9, and UGT2B7 in the liver, and by UGT1A1, UGT1A3, and UGT2B7 in the intestine |
2.4.1.17 | 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid + UDP-glucuronate |
glucuronidation of 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid is mainly catalyzed by UGT1A1, UGT1A9, and UGT2B7 in the liver, and by UGT1A1, UGT1A3, and UGT2B7 in the intestine i humans |
2.4.1.17 | 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid + UDPglucuronate |
glucuronidation of 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetic acid is mainly catalyzed by UGT1A1, UGT1A9, and UGT2B7 in the liver, and by UGT1A1, UGT1A3, and UGT2B7 in the intestine in humans |
2.4.1.17 | 21-hydroxyprogesterone + UDP-glucuronate |
- |
2.4.1.17 | 6alpha-hydroxyprogesterone + UDP-glucuronate |
- |