EC Number |
Natural Substrates |
---|
2.4.1.101 | more |
enzyme initiates the biosynthesis of heparan sulfate |
2.4.1.101 | more |
GLY-13 plays an important role in the synthesis of N-glycans. Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylglucosaminidase |
2.4.1.101 | more |
the enzyme catalyzes the first step in the conversion of oligomannose to complex or hybrid N-glycans of glycoproteins |
2.4.1.101 | more |
the enzyme is essential for processing of high-mannose to hybrid and complex N-glycans |
2.4.1.101 | more |
transformant plants that exhibit specific reduction of GnTI activity below detection limit, do not exhibit significantly altered complex N-glycan structures. Even the undetectable residual GnTI activity is sufficient for the synthesis of complex N-glycans comparable to wild-type plants |
2.4.1.101 | UDP-N-acetyl-alpha-D-glucosamine + Man5GlcNAc2-[protein] |
- |
2.4.1.101 | UDP-N-acetyl-D-glucosamine + 3-(alpha-D-mannosyl)-beta-D-mannosyl-R |
- |
2.4.1.101 | UDP-N-acetyl-D-glucosamine + 3-(alpha-D-mannosyl)-beta-D-mannosyl-R |
GlcNAc transfer catalyzed by GnT-I is the first step in the conversion of high mannose oligosaccharides to complex and hybrid N-glycan structures |
2.4.1.101 | UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl-Asn-peptide |
stimulates galactosyltransferase of bovine milk |
2.4.1.101 | UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-alpha-D-mannosyl-1,6-(alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-1,4-N-acetyl-D-glucosaminyl-Asn-peptide |
key enzyme of biosynthesis of complex and hybrid N-glycans |