EC Number   |
Natural Substrates |
|---|
   2.3.1.97 | more |
ablating NMT1 is more effective in inhibiting tumor growth than is ablation of NMT2 |
| 2.3.1.97 | more |
NMT1 is critical for tumor cell proliferation. Ablating NMT1 is more effective in inhibiting tumor growth than is ablation of NMT2 |
| 2.3.1.97 | more |
isozyme NMT1 catalyzes myristoylation of various proteins crucial in signal transduction, cellular transformation, and oncogenesis |
| 2.3.1.97 | more |
isozyme NMT2 catalyzes myristoylation of various proteins crucial in signal transduction, cellular transformation, and oncogenesis |
| 2.3.1.97 | more |
presence of approximately 60 putative N-myristoylated proteins encoded by the Trypanosoma brucei genome |
| 2.3.1.97 | more |
strong interaction of NMT2 with caspase-3 with a probable major role in the cellular regulation of NMT2, caspase-3 interaction with NMT2 is stronger than with NMT1. The cellular regulation of NMT1 and NMT2 is mediated by two different signaling molecules, m-calpain and caspase, respectively, overview. Protein-protein interaction of NMT forms and p53 |
| 2.3.1.97 | more |
the enzyme catalyzes the cotranslational irreversible addition of a fatty acyl moiety to the N-terminus of proteins |
| 2.3.1.97 | myristoyl-CoA + glycylpeptide |
- |
| 2.3.1.97 | myristoyl-CoA + glycylpeptide |
specific for Gly at N-terminus |
| 2.3.1.97 | myristoyl-CoA + glycylpeptide |
essential for growth |
