EC Number |
Natural Substrates |
---|
2.3.1.65 | choloyl-CoA + glycine |
- |
2.3.1.65 | choloyl-CoA + glycine |
conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct |
2.3.1.65 | choloyl-CoA + glycine |
conjugation of bile acids with glycine or taurine favors their excretion into bile and uptake from portal blood into the liver, it promotes absorption of fat and fat-soluble vitamins in the acidic environment of the small intestine by lowering the pKa of the bile acids and hence maintaining its solubility |
2.3.1.65 | choloyl-CoA + glycine |
taurine can replace glycine, involved in conjugation of bile acids |
2.3.1.65 | choloyl-CoA + glycine |
cholesterol degradation, glycine conjugates of bile acids occur in adult |
2.3.1.65 | choloyl-CoA + taurine |
- |
2.3.1.65 | choloyl-CoA + taurine |
conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct |
2.3.1.65 | choloyl-CoA + taurine |
conjugation of bile acids with glycine or taurine favors their excretion into bile and uptake from portal blood into the liver, it promotes absorption of fat and fat-soluble vitamins in the acidic environment of the small intestine by lowering the pKa of the bile acids and hence maintaining its solubility |
2.3.1.65 | choloyl-CoA + taurine |
taurine can replace glycine, involved in conjugation of bile acids |
2.3.1.65 | choloyl-CoA + taurine |
cholesterol degradation, bile acids are secreted as taurine conjugates in fetus and neonatus |