EC Number |
Natural Substrates |
---|
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + a sphingoid base |
- |
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + a sphingoid base |
C26-C34 |
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + a sphingoid base |
C26-C36 |
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + a sphingoid base |
the enzyme exhibits a broad acyl chain preference synthesizing C26-C32 acyl chain ceramides |
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + phytosphingosine |
- |
2.3.1.298 | an ultra-long-chain fatty acyl-CoA + sphingosine |
the enzyme uses acyl-CoAs longer than 26 carbon atoms in length |
2.3.1.298 | fatty acyl-CoA + dihydrosphingosine |
- |
2.3.1.298 | more |
CERS3 transfers much longer chain fatty acids (C26, C28), forming highly hydrophobic ceramides that are a very important part of the water barrier function of skin |
2.3.1.298 | sphingosine + behenoyl-CoA |
- |
2.3.1.298 | sphingosine + cerotoyl-CoA |
- |