EC Number   |
Natural Substrates |
|---|
   2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet |
- |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
keeps in store initiator tRNAfMet for initiation of protein synthesis |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
involved in initiation of protein biosynthesis |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
involved in initiation of protein synthesis in chloroplasts, other mechanism than in cytoplasm of eukaryotes |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
formyl group provides a positive determinant for IF2, which can select the initiator fMet-tRNA from other tRNAs and a negative determinant, which blocks the binding of EF-Tu to the initiator tRNA |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
component of a protein chain initiating system in chloroplasts |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
initiation of protein synthesis in mitochondria |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
enzyme reaction irreversibly commits methionyl-tRNAfMet to initiation of translation in eubacteria |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
key step in the targeting of initiator tRNA towards the translation start machinery in prokaryotes |
| 2.1.2.9 | 10-formyltetrahydrofolate + L-methionyl-tRNAfMet + H2O |
formylation of the methionyl-tRNA-fMet is essential for in vitro binding of imported formylated elongator-type tRNA(Met) |
