EC Number |
Natural Substrates |
---|
2.1.1.77 | more |
PIMT level is downregulated by proteasomal degradation, involving the PI3K pathway, during cell attachment. The regulation of PIMT level upon cell-substratum contact suggests a potential role for PIMT in biological processes such as wound healing, cell migration, and tumor metastasis dissemination |
2.1.1.77 | more |
protein L-Asp and protein D-isoaspartate are no substrates |
2.1.1.77 | S-adenosyl-L-methionine + acid trehalase D-aspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + histone H4 D-aspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + plant RNA helicase 75 L-isoaspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + protein D-aspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + protein D-isoaspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + protein L-isoaspartate |
- |
2.1.1.77 | S-adenosyl-L-methionine + protein L-isoaspartate |
implicated in the repair or degradation of age-damaged proteins that contain atypical L-isoaspartyl residues |
2.1.1.77 | S-adenosyl-L-methionine + protein L-isoaspartate |
post-translational covalent modification |