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Results 1 - 8 of 8
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.3603 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 overall reaction
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360more AF10 bound to the enzyme simultaneously senses unmodified histone H3 lysine 27 via its PHD finger-Zn knuckle-PHD finger domain and enables the enzyme to methylate histone H3 at lysine 79. Knockout embryos, lacking Af10, have reduced [histone H3]-N6-methyl-L-lysine79 in developing nasal processes and reduced expression of AP2alpha, a gene required for cranial neural crest cell development
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-L-lysine79 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine79 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine79 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + histone L-lysine -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + [histone H3]-L-lysine79 -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine79 -
Results 1 - 8 of 8