EC Number   |
Natural Substrates |
|---|
    2.1.1.20 | more |
all-trans-retinoic acid and dexamethasone independently induce GNMT in liver, no effect on enzyme from pancreas |
| 2.1.1.20 | more |
interaction of benzo(a)pyrene with the enzyme may contribute to carcinogenesis |
| 2.1.1.20 | more |
major folate binding protein |
| 2.1.1.20 | more |
major folate binding protein, interacts with environmental carcinogens such as benzo(a)pyrene |
| 2.1.1.20 | more |
major folate binding protein, involved in the regulation of the expression of S-adenosylhomocysteine hydrolase and formiminotransferase cyclodeaminase, binds benzo(a)pyrene and prevents DNA-adduct formation |
| 2.1.1.20 | more |
a mammalian target of rapamycin (mTOR) inhibitor (DEP domain containing MTOR-interacting protein [DEPDC6/DEPTOR]) is identified as a GNMT-binding protein by using yeast two-hybrid screening. The C-terminal half of GNMT interacts with the PSD-95/Dlg1/ZO-1 (PDZ) domain of DEPDC6/DEPTOR |
| 2.1.1.20 | S-adenosyl-L-methionine + glycine |
regulates the ratio of S-adenosylmethionine to S-adenosylhomocysteine |
| 2.1.1.20 | S-adenosyl-L-methionine + glycine |
the enzyme regulates the methyl group supply for S-adenosylmethionine-dependent transmethylation reactions. All-trans-retinoic acid rapidly induces glycine N-methyltransferase in a dose-dependent manner and reduces circulating methionine and homocysteine levels in rats |
| 2.1.1.20 | S-adenosyl-L-methionine + glycine |
key regulatory enzyme for methyl group metabolism by regulating the S-adenosyl-L-methionine/S-adenosyl-L-homocysteine ratio |
| 2.1.1.20 | S-adenosyl-L-methionine + glycine |
key enzyme for the regulation of the ratio of S-adenosylmethionine to S-adenosylhomocysteine |
