EC Number |
Natural Substrates |
---|
1.8.1.7 | glutathione disulfide + NADPH |
- |
1.8.1.7 | glutathione disulfide + NADPH |
antioxidant enzyme, protects the pancreatic cell against reactive oxygen species involved in the diabetogenic agent-induced dysfunction of pancreatic-beta-cells |
1.8.1.7 | glutathione disulfide + NADPH |
enzyme is required for disposal of peroxides and radicals especially in the brain |
1.8.1.7 | glutathione disulfide + NADPH |
enzyme produces glutathione in spermatozoa which is required for reduction and antioxidant defense by glutathione peroxidase, enzyme is involved in protection of the cells against oxidative damage, regulatory of pentose phosphate pathway, pathway overview |
1.8.1.7 | glutathione disulfide + NADPH |
key enzyme in maintaining the reducing environment in the cell, maintainance of sulfhydryl redox potential in the cytoplasm |
1.8.1.7 | glutathione disulfide + NADPH + H+ |
- |
1.8.1.7 | glutathione disulfide + NADPH + H+ |
the enzyme is an important oxidoreductase that helps maintain redox homeostasis |
1.8.1.7 | GSSG + NADPH |
- |
1.8.1.7 | GSSG + NADPH |
high intracellular concentration of glutathione is important for functionality of thiol groups of cellular proteins |
1.8.1.7 | GSSG + NADPH |
maintenance of glutathione/GSSG ratio is a protective mechanism for intracellular thiols during growth in atmospheric oxygen |